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In one study, headlice collected from individuals in Senegal who were experiencing treatment failure were genotyped and compared to a reference strain of body lice that were never exposed to ivermectin

The age-related decline in neuromodulator levels, combined with the less-significant learning and memory effects from PXN LOW in aged animals (though a trend was noted, P = 0.07), may explain the reduced cognitive benefits of both caffeine and paraxanthine in older individuals

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