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Healthcare providers must review a patients medication list for any antidepressants, stimulants, or other psychoactive drugs before initiating MB, and appropriate washout intervals (e.g., 2 weeks for most SSRIs, longer for fluoxetine) are advised if MB is needed

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For instance, AAV9-mediated delivery of the very longchain acylCoA dehydrogenase (VLCAD) gene was used to treat very long-chain acyl-CoA dehydrogenase deficiency, directly correcting the -oxidation defect and maintaining stable cardiac function for up to 6 months in mice (Keeler et al., 2012)

Carbon dioxide level Several other environmental factors on the ISS have been proposed to contribute to SANS (Fig