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You are not a candidate for GLP-1 medications if you have: A personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN2) A history of pancreatitis or severe gallbladder disease Active pregnancy or are breastfeeding Type 1 diabetes (without specific provider guidance) Severe gastrointestinal disorders, certain eating disorder histories, and a few other conditions may also disqualify you
Financial disclosure The authors declare no competing financial interests
Inflammation in T2D is primarily triggered by cytokines and adipokines released by adipocytes, including IL-6, TNF-, resistin, visfatin, angiotensin, adiponectin, leptin, monocyte chemoattractant protein-1 (MCP-1), and plasminogen activator inhibitor-1 (PAI-1)
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Xenin is another gut-derived food-induced peptide known to potentiate GIP activity (222, 223)
