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In the future, targeting amino acid metabolic pathways may become a new strategy for regulating macrophage polarization, promoting neural repair, and limiting inflammatory damage

Initially focused on metabolism, research showed NNMT elevation with age/weight leads to fat accumulation, inefficiency, and NAD+ loss.[30][31] High NNMT correlates with insulin resistance and obesity in humans

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Unlike previous studies, we conduct a systematic review of all known SLC molecules potentially involved in these processes (summarized in Tables 1 and 2), 19156 emphasizing their clinical applications or potential