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Among these, so-called resistant -cells maintain high INS, MAFA, and PDX1 expression under diabetic conditions, preserving function despite hyperglycemia and inflammation ( 2.1 Functional -cell subtypes in health and T2D Recent research has shifted from establishing -cell heterogeneity to defining the specific functional roles of its subpopulations

Related to their favorable effect on gut microbiota, both seem to reduce inflammation, decrease some risk factors for cardiovascular disease, enhance satiety and promote weight loss and improve the bioavailability of minerals [298, 299]

However, regardless of the look of the body, patients often feel the difference in their everyday lives

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doi: 10.3390/ijms161226138 271 LloydSMArnoldJSreekumarA