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Cell culture studies have shown that NNMT inhibition increases intracellular NAD+ levels, enhances sirtuin activity, and shifts adipocyte metabolism toward greater fatty acid oxidation

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J AOAC Int 91:13091317 Benitez FJ, Acero JL, Real FJ et al (2013) Photolysis of model emerging contaminants in ultra-pure water: kinetics, by-products formation and degradation pathways