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Participants Two cohorts were constructed: Cohort 1 Incident GLP-1 RA users for whom GLP-1 RA treatment was first initiated with the medications of interest during the study selection window

Melatonin overdose is generally not considered life-threatening, but taking excessive amounts can lead to prolonged sedation and other uncomfortable side effects

Wegovy is an FDA-approved finished product manufactured by Novo Nordisk that has undergone FDA review for safety, effectiveness, and quality

This includes your GP, a pharmacist, or an online doctor through a regulated service like Asda Online Doctor

After the first four weeks, your healthcare provider may increase the dose to 0.5 mg every week for the next four weeks, especially in patients with chronic kidney disease