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thus, B12 deficiency causes a functional folate deficiency known as the folate trap (Bender 2003)

In Europe, the European Food Safety Authority (EFSA) requires formal evaluation and approval of health claims under Regulation (EC) No 1924/2006, while nanoformulations or novel delivery systems often fall under the Novel Food Regulation (EU 2015/2283), requiring comprehensive safety and toxicological data

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Your prescriber may delay increases if you are experiencing side effects or achieving good results at a lower dose