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At 6 months, mean GSH levels increased 3035% in erythrocytes, plasma, and lymphocytes and 260% in buccal cells in the high-dose group

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We also observed increased aggregate formation following incubation of the GST fusion proteins with cell lysate, which appears to depend on both the cell type and experimental conditions

This includes the development of inhibitors of IkB kinases (IKKs), NF-kB-inducing kinase and IkB ubiquitin ligase, which regulate the activity of NF-kB and inhibit the degradation of IkB [135,136]