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Key takeaway: Methyl B12, the kind found in the New Results sublingual B12 Super Shot spray, is natural and shown to be absorbed much better than cheaper, synthetic B12 supplements

While age and sex cannot be modified, knee OA is strongly associated with lifestyle factors that can be controlled

When B12 may be relevant B12 status can be relevant for tiredness, dietary restriction, absorption issues, or previous deficiency, but symptoms should be considered in context rather than assumed to be B12-related

Watch-outs to know: Some researchers have discussed concerns that repeatedly stimulating reproductive hormones could create long-term health consequences

The cause of the disease is not clear, but genetic factors related to the polymorphism of the HLA-Cw6 gene are most often indicated