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Its mechanism involves stimulating natural GH release specifically to reduce visceral adipose tissue, with research originally focused on HIV-associated lipodystrophy

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5 There are genotypephenotype correlations in that individuals with haploinsufficiency tend to have a milder phenotype 6,7 and splice-site variants are associated with a more severe phenotype

Ligands are cellproduced molecules that interact with their receptors similarly to how puzzle pieces fit together, as depicted in Figure 7