The test identifies key variants including GLP1R rs6923761 (GLP-1 receptor sensitivity), GIPR rs1800437 (GIP pathway activation), FTO rs9939609 (metabolic setpoint), and MC4R rs17782313 (hunger regulation)
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US Food and Drug Administration, Center for Drug Evaluation and Research
The potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes: a randomized controlled trial exploring weekly, biweekly, and monthly dosing [abstract]
Researchers used an indirect comparison to evaluate their relative efficacy in patients with T2D inadequately controlled on metformin monotherapy, with change in HbA1c and body weight at approximately one year as the primary outcomes