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Journal of Biomedical Informatics 2009;42:377381

SAMe is found in every living cell and has been commonly used as a dietary supplement since 1952

Initially, 32 clinical study records were retrieved

Drug design, development and therapy , 9 , 24852499

Also, the microglia are implicated in many illnesses of the brain and contribute both as a protector of neural tissues, and also as a source of pro-inflammatory cytokines that disrupt the BBB (Thurgur and Pinteaux, 2019