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Semaglutide is highly protein-bound and is not expected to be removed by dialysis

Pharmacokinetics Absorption Absolute bioavailability of semaglutide is 89%

It functions to help regulate glucose levels in a manner similar to the GLP-1 hormone that your stomach naturally releases after eating

A realistic timeline for appetite changes Semaglutide is started at a low dose and stepped up over several weeks

Seek emergency medical attention immediately (call 999 or attend A&E) if you experience: Sudden breathing difficulty, wheezing, or throat tightness potential signs of anaphylaxis Rapid swelling of the face, lips, tongue, or throat (angioedema) Feeling faint, dizzy, or collapsing may indicate hypotension Rapidly progressive widespread urticaria developing after injection Severe abdominal pain or persistent vomiting These symptoms may indicate a severe allergic reaction (anaphylaxis), which requires urgent treatment with intramuscular adrenaline and supportive care