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Pathological changes may occur at the level of the cochlea, auditory nerve, brainstem, or auditory cortex and can involve injury to hair cells, cochlear synapses, spiral ganglion neurons, or the stria vascularis

The fast reactivity of PAT was confirmed in vivo and in vitro where no PAT could be detected in human serum after ingestion of PAT containing apple juice and a reduction of PAT levels by 94% within two minutes of incubation of PAT in a human blood sample (Rychlik 2003)

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doi: 10.3389/fnut.2023.1209614 [DOI] [PMC free article] [PubMed] [Google Scholar] 189.Fan L, Guan F, Ma Y, Zhang Y, Li L, Sun Y, et al