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For patients at moderate risk of rhabdomyolysis who are at low risk of fluid overload, consider empiric IV fluid administration (e.g., D5LR at 150 ml/hr)

Before Treatment Patients should consult a licensed healthcare provider to review their medical history

Summary: Macrogol (polyethylene glycol) preparations such as Laxido and Movicol are generally considered the most effective stool softeners for GLP-1 users, as they are well-tolerated for long-term use and particularly suitable for chronic constipation

Gradual Initiation and Monitoring: Both medications typically begin with a gradual initiation plan customized by a healthcare provider

non-GLP-1 use and vs