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(6) Nitric oxide is crucial for erections because it signals blood vessels to relax and widen, allowing more blood to flow into erectile tissue

Improves mitochondrial biogenesis Increases energy production Enhances fat oxidation Reduces fatigue Supports insulin sensitivity Boosts workout performance Reduces metabolic slowdown associated with aging MOTS-C appears to influence: AMPK activation (metabolic switch) Glucose utilization Fat metabolism pathways Oxidative stress response Mitochondrial DNAlinked signaling This makes MOTS-C a foundational option for adults using peptide therapy over 40 for energy, metabolism, and overall vitality

Dietary modifications and gradual dose titration are the recommended first-line approaches per NICE guidance

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Functional Medicine 2.0 Perspective Under FM 2.0, the focus is on precision repair, not symptom suppression