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Epigenetic modifications affecting long-term gene expression DNA methylation changes: GHK-Cu may affect DNA methyltransferase activity altering cytosine methylation patterns

Moreover, to validate the results, the experimental procedures were repeated three times at a 2-week interval in the same conditions

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Further, the numbers were 35% from anti-estrogenic substances (tamoxifen, clomiphene, fulvestrant, toremifene, and raloxifene) and 20% from AIs (letrozole, anastrozole, exemestane, adrostatrienedione, and armistane) in 2022 (World Anti-Doping Agency, 2024b)

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