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~ AlphaMD Updated on July 23rd, 2025 Hormonal imbalances can have a significant impact on reproductive health, energy levels, and overall well-being

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A recent review highlights that clascoterone cream 1%, FDA-approved in 2020 for patients 12 years, is supported by robust Phase III randomized controlled trials demonstrating both efficacy and safety

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According to the Phase 2 trial published in the New England Journal of Medicine , retatrutide achieved weight reductions up to 24.2% at 48 weeks , with projections nearing or exceeding 25% at full duration (Coskun et al., 2023)