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All of our experiments were performed in male mice

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Variants and their proxies from these analyses were checked for associations with indices of insulin secretion and related phenotypes in cohorts including the Botnia study (n=9210) from Western Finland, the Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) as well as Integrated Network for Systematic analysis of Pancreatic Islet RNA Expression Consortium (INSPIRE)