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Dosing Protocol Reference microgram doses from the Symlin label, converted to U-100 units at 2 mg/mL (20 mcg per unit)

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The kinetic data can be best explained by a ternary complex in which PfGrx recruits and activates GSH at the 1st glutathione-interaction site to facilitate the rate-limiting glutathionylation of roGFP2 WT (S 2 ) and its subsequent deglutathionylation in accordance with monothiol mechanism (iii) from Fig