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Abstract Glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists and tirzepatide, a dual GLP1R and glucose-dependent insulinotropic polypeptide receptor agonist, have become fundamental in managing type 2 diabetes mellitus (T2DM) and obesity due to their potent glycaemia-lowering and weight-lowering effects as well as their cardiovascular and renal benefits

4.2 Effects on the female reproductive system Melatonin also significantly affects the female reproductive system, influencing oocyte maturation, cumulus cell expansion, and the production of steroid hormones

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