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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

BPC 157 has also been studied via oral and intraperitoneal routes, particularly in GI repair models

Under normal conditions in living organisms oxygen metabolism (above all reduction) leads to the formation of highly reactive intermediates called reactive oxygen species (ROS) that are dangerous for the cell (Yu, 1994)

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Another achievement of this study was the fact that we successfully established a BBB in vitro model, a tight endothelial barrier using hydrocortisone-treated b.End3 cells, to evaluate nanoformulations (Fig