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Collectively, these findings enhance our understanding of the structural linkage across the cell membrane and provide a foundation for the molecular interpretation of many muscular dystrophy-related mutations

The trending decline in the junctional zone could be affecting the labyrinth layer, as placentas with decreased spongiotrophoblasts and glycogen cells (both found in the junctional zone) are shown to induce decreased proliferation and a surge in apoptosis in the labyrinth layer [50, 61]