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Described as a disorder of glucose homeostasis and insulin sensitivity, it is primarily triggered by uncontrolled hyperglycemia, and it is responsible for a large number of microvascular (like diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy) and macrovascular complications (like diabetic foot syndrome, cerebrovascular events, and myocardial infarction) [5]

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In contrast to ASCT2, ATB0,+ catalyzes unidirectional influx of substrates into cells [41]

This study has shown that PLGA nanoparticles can exploit lipid raft-mediated pathways for cellular entry, often in a non-specific manner [204]