5-Oxoprolinase deficiency is a very rare autosomal recessive disease characterized by 5-oxoprolinuria, and a very heterogeneous clinical presentation, including renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly (Njalsson and Norgren, 2005
10.1159/000045293 133 SakaguchiY.HamanoT.WadaA.MasakaneI
The associations were strongest for liver, lung, pancreatic cancers, and myeloid malignancies
So, then if you do the statistics to see what percentage of Americans are falling short using the updated RDAs that actually reflect our current body weights, it would be close to 100% of Americans that are falling short of magnesium
Your health isn't a one-size-fits-all situation, so your treatment plan shouldn't be either