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We demonstrate that mGIPR-Ab/GLP-1 peptideantibody conjugates act on CNS GIP and GLP-1 receptors via CVOs to activate neural pathways, enabling the reduction of food intake and weight loss in obese mice

If you experience symptoms of the following adverse effects, stop taking semaglutide and contact your healthcare provider: Thyroid tumors: Semaglutide may increase the risk for certain types of thyroid tumors including medullary thyroid cancer or multiple endocrine neoplasia syndrome 2 (MEN2)

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McGurnaghan SJ et al.: Development and validation of a cardiovascular risk prediction model in type 1 diabetes