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GLP-1R agonists are tailored to emulate the effects of the hormone GLP-1, secreted from the L cells in the distal portion of the small intestine [41], which causes a reduction in glucagon release, suppression of the hypothalamic hunger center, and slowing of gastric emptying (Figure 3)

Injections must be administered in office and can not be dispensed

Add an appropriate volume of BAC water to the vial and allow the peptide to dissolve by gently swirling do not shake, vortex, or agitate vigorously, as mechanical stress may degrade peptide integrity

By learning about semaglutides mechanisms of action, preparing for injection, selecting an appropriate injection site, executing the procedure step-by-step, managing potential side effects, and educating your patients on adherence strategies youll be able to optimize outcomes for those under your care