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Eating too little can trigger headaches through multiple mechanisms, including low blood sugar, electrolyte imbalances, and muscle tension

Clinical oversight is built around the no-auto-refill model: you reorder when you need medication, and a provider reviews your file before each fill

When your medication arrives, refrigerate it immediately

Note the time and factor it into your remaining room temperature budget if you plan to be without refrigeration again

In multiple-dose clinical trials involving more than 5000 patients, four patients discontinued therapy because of treatment-related liver enzyme abnormalities and one because of a renal function abnormality