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This may influence several physiological functions including, but not restricted to, lowering both pre- and afterload of the heart and downregulation of sympathetic activity, and decreased intraglomerular pressure which is believed to be mediated by increased tubuloglomerular feedback

GLP-1 receptor agonists, once primarily prescribed for Type 2 Diabetes, have evolved into a multi-billion-dollar therapeutic category reshaping obesity treatment, cardiovascular care, metabolic health, and potentially even neurological disorders

OConnor DB, Ferguson E, Green JA, OCarroll RE, OConnor RC