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This interaction is significant in research exploring calmness, sleep induction, and nervous system regulation

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Furthermore, the weight loss induced by tirzepatide appears to be primarily due to a greater reduction in fat mass compared to metabolically active lean mass, resulting in a favorable redistribution of abdominal ectopic adipose tissue and a marked reduction in waist circumference and intrahepatic fat [54]

Ethics declarations Competing interests PCh and PCl have received research support and honoraria as speakers and consultants from Merck Serono