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We need more clinical trials examining the cardiac benefits of SGLT2 inhibitors and GLP-1 agonists for patients prescribed insulin, but with more information on diabetes control and the extent of that benefit provided as the diabetes control is worse. For more information: Joanna Khatib, MBBS , can be reached at [email protected].

The results showed improved cochlear hair cell regeneration, synaptic restoration, and tinnitus score reduction in over 72% of patients

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Oxidative stress can be caused by elevated levels of sugar in the blood (hyperglycemia), as well as insulin deficiency or resistance

Nrf2 and HO-1 are transcription factors that contribute to the cellular response to oxidative stress and cytokines release, thus protecting tissues against redox status [73]