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Nevertheless, these shortcomings do not fundamentally invalidate the concept

As wound healing is essential to tissue integrity and overall health, the care and management of chronic wounds in aging populations have become a critical public health concern, annual cost of treating chronic wounds, including various ulcers, are estimated to reach up to $96 billion in the U.S

and regulation of T cell activation

However, prolonged use of painkillers has led to the development of opioid addiction, which has been linked to the reward processes, one of the primary functions of opioids (Pellissier et al

Cosmoderma Lim HW, et al