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Yes, melanotan-1 dosing must account for cumulative melanocortin receptor activation
Figure 7 Cell Apoptosis and DNA Fragmentation At 13 weeks, there were no significant changes in capase-3 and TUNEL positive cell numbers among the three female experimental groups, although cortex capase-3 and TUNEL positive cells in the SE offspring were more than doubled than the SHAM offspring (Figures 8D,H)
A consideration for people needing IV GSH and HDIVC within a 24 hour period would be that HDIVC distributes through and stays in Plasma much longer than IV GSH so if one must administer GSH and HDIVC within a 24 hour period administration of the GSH should be done prior to (and not after) HDIVC to minimize crossover
Glutathione takes 812 weeks to produce visible lightening vs hydroquinone's 46 weeks
