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Greenfield B

These epidemiological trends have accelerated the development of pharmacological strategies capable of inducing sustained weight reduction

This is why the diagnosis of low testosterone is not based on a simple blood test but includes a number of assessments, including a full medical history, physical examination and other tests

When tested as a once-daily injection in single and multiple doses varying up to 0.18 mg in healthy normal to overweight volunteers, gastrointestinal adverse events (nausea, diarrhoea, constipation, vomiting) were encountered, but the drug was described as well tolerated

Whether this is three per year or a course of three or three in a lifetime is not at all clear and left to individual clinicians judgement and experience