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Targeted MRM-based methods are most easily developed with the availability of purified proteins, whereas untargeted DDA analyses offer a more flexible, universal application without time-consuming optimization steps

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CoQ10 is a naturally occurring antioxidant found in the cells of the heart, liver, and kidneys

Genetic factors associated with serum UA can be used as an explicit proxy for serum UA concentration, permitting the assessment of its potential causal relationship with PD, a technique referred to as Mendelian randomisation (MR)