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Most research focused on short-to-medium term use (days to weeks)

It can improve skin tecture, color tone and appearance reduce the appearance of acne/defects, resist moisture, help reduce the appearance of fat, reduce blackheads, wrinkles, fine lines, black spots

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31,35-37 Prospective trials are needed to further explore this potential adverse event and worsened DR, which is the central premise of the ophthalmic FOCUS trial that is expected to release results in 2026

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