How Key Electrolytes Are Affected by GLP-1 Use Researchers havent investigated the exact effects a GLP-1 RA medication might have on electrolytes, let alone the different versions
DOI: 10.1016/j.joca.2024.06.011 [Google Scholar] Nanus DE, Badoume A, Wijesinghe SN, Halsey AM, Hurley P, Ahmed Z, et al
While the clinical significance of this in healthy adults is still being characterised, the theoretical concern about sustained supraphysiological IGF-1 and long-term tissue effects is the basis for the oncogenic risk concerns flagged in the long-term safety literature
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ATP evoked currents were also detected by sniffer patches placed in close proximity to primary L-cells following stimulation by various agonists of nutrient-sensing receptors expressed on L-cells including AMG-1638 (10 M), a selective free-fatty acid receptor 1 (FFA1) agonist, GPBAR-A (10 M), a selective agonist of the bile acid receptor GPBAR1, and peptones (3 mg ml 1