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Value of 11C-choline PET/CT for lung cancer diagnosis and the relation between choline metabolism and proliferation of cancer cells

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After blocking with 5% BSA, the sections were incubated with 1:200 anti-GLP-1 (ab23468, Abcam), followed by detection with secondary antibodies Alexa Fluor 488 conjugated goat antibody to mouse IgG (A-11029, ThermoFisher

While Lipinskis Rule of Five suggested that molecules with a molecular weight less than 500 Da have better chances of crossing the BBB than larger molecules, its essential to note that Lipinski himself cautioned against applying these rules to certain categories of molecules, such as anti-parasitic drugs