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Impaired thymidylate synthesis, which leads to faulty DNA synthesis, is responsible for megaloblastic and macrocytic anemias
Control groups of mice were maintained on LD or WD and given sham (10 mL/kg body weight sterile saline) injections throughout the study (termed LD/LD-V, or LD control, and WD/WD-V, or WD control, groups
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These injections may be given a few times per week
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