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Mutations in LRRK2 linked to parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

Wegovy is FDA-approved for chronic weight management in adults and pediatric patients aged 12 years and older with obesity (BMI 30 kg/m for adults, 95th percentile for age and sex in pediatrics) or overweight (BMI 27 kg/m for adults, 85th percentile for pediatrics) with at least one weight-related comorbidity