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However, a significant challenge is the non-specificity of broad-spectrum HDAC inhibitors, which can lead to off-target effects and side effects by affecting acetylation states in numerous cell types and tissues beyond the auditory pathway, limiting their clinical utility for a condition like tinnitus

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GLP-1 receptor agonists and the risk of postoperative nausea and vomiting after laparoscopic sleeve gastrectomy: a single-center, retrospective cohort study