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10.3390/brainsci13101453 Brain Sci

This is the first step toward developing that knowledge, which will require large-scale, carefully controlled clinical trials. Rasgon is a member of the Stanford Neurosciences Institute

The initial formations of -ketoglutarate from glucose do require malateaspartate cycle activity, but there seem to be agreement that only 1520% of glutamineglutamate (GABA) cycle activity is connected with de novo synthesis of glutamate