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watch now Cigna CEO on medicare advantage and GLP-1 access program Cigna CEO David Cordani joins 'The Exchange' with CNBC's Bertha Coombs to discuss the company's growth opportunity in services, Cigna's GLP-1 access program, and more

The liberated N-terminal fragment of GSDMD (GSDMD-N) oligomerizes within the plasma membrane to form pores, leading to pyroptotic cell death 52

This is consistent with a mechanism where the R471-carboxylate interaction is required to couple substrate binding to transport

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