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He hypothesized that lactic acidosis, increased concentration of Krebs cycle metabolites in urine, reduced levels of carnitine in plasma, decreased utilization of glucose in the brain, and lowered ATP levels in these patients are associated with mitochondrial dysfunction [66]

FDA-approved GLP-1 medications are available in injectable form (weekly subcutaneous injections, like Wegovy and Zepbound) and oral form (daily tablets, like Wegovy oral and the newly FDA-approved Foundayo, which contains orforglipron)

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Learn how this type 2 diabetes medicine has turned into a great drug for other conditions