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Symptoms of vitamin B12 deficiency Some of the symptoms that can be caused by a lack of vitamin B12 include: Poor appetite Anemia Fatigue Weakness Numbness or tingling in the hands or feet Difficulty with balance Vitamin B12 deficiency can also contribute to depression, cognitive impairment, and dementia

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Safety and Product-Quality Uncertainties There is no mature human safety record for 5-Amino-1MQ

GLP-1 receptor agonists such as Saxenda and Wegovy work, with clinical trial evidence behind them roughly 6% and 16% body weight reduction respectively over 68-week trials

Additionally, B12 increased the mRNA levels of HGF in the impaired group compared to the non-impaired group incubated with the excipient ( P = 0.0081)