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As of early 2025, a systematic review of the musculoskeletal literature identified 544 published BPC-157 articles from 1993 to 2024, of which 36 focused on orthopaedic outcomes and only one was a human clinical study [16]

[81] The decline in cellular concentrations of NAD + during aging likely contributes to the aging process and to the pathogenesis of the chronic diseases of aging

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