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Societal and Economic Impact In less than five years, GLP-1-based drugs have leapt from obscure endocrinology clinics to the front pages of celebrity magazines

Ensure adequate nutrition despite reduced appetitesemaglutide significantly decreases hunger, but severe caloric restriction can worsen menstrual irregularities

Both medications have demonstrated safety profiles across multi-year clinical trials

The obesity treatment market, driven by unprecedented demand for effective weight-loss therapies, has been dominated in recent years by GLP-1 receptor agonists such as Zepbound and competitors like Novo Nordisks Wegovy

For a more affordable weight-loss program, read our list of the cheapest online GLP-1 programs