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Lipases achieve an open state by undergoing interfacial activation, which occurs when the lipase associates with a nonpolar-aqueous interface 30

Patient Educ Couns 73(3):465472

13 Historically the term osteochondritis dissecans was described in 1887 by Knig, who hypothesized an inflammatory genesis at the interface between cartilage and subchondral bone, but subsequent studies have disproved this hypothesis and the exact pathophysiology remains unclear at present

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To determine how an overall planar geometry might impact photodeprotection rates, fused ring analogs were made from triazole-bridged 1,5-diaryl precursors possessing 2-bromophenyl reactive groups using a Pd-catalyzed annulation reaction