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At the same time, the authors also found that GSH content in 4T1 cells was sharply cut down owing to Glud-MFo-c GSH-depletion ability (Figure 6C), which effectively amplified Ce6-produced 1 O 2 accumulation, and provided a potential method to combat cancer

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On the other hand, similar DNA protective action has been found also in the case of other polyphenols, e.g., quercetin, that decreased the levels of 8-hydroxydeoxyguanosine in kidney or liver cells following their exposure to oxidative stress 157,158,159